Propofol effective concentration 50 and its relationship to bispectral index
نویسندگان
چکیده
منابع مشابه
Effect of remifentanil on plasma propofol concentration and bispectral index during propofol anaesthesia.
BACKGROUND Propofol and remifentanil are commonly administered together in clinical anaesthesia, but the effect of remifentanil on the plasma concentration of propofol has yet to be established. The aim of the present study was to investigate the effect of remifentanil on plasma propofol concentrations (Cp) in the absence of surgical stimulation. METHODS Thirty-eight patients undergoing elect...
متن کاملBispectral index monitoring during sedation with sevoflurane, midazolam, and propofol.
BACKGROUND Bispectral Index (BIS) has been used to measure sedation depth. Ideally, to guide anesthetic management, range of BIS scores at different sedation levels should not overlap, and BIS should be independent of drug used. This study assessed ability of BIS to predict sedation depth between sevoflurane, propofol, and midazolam. Quality of recovery was also compared. METHODS Patients und...
متن کاملRelationship between calculated blood concentration of propofol and electrophysiological variables during emergence from anaesthesia: comparison of bispectral index, spectral edge frequency, median frequency and auditory evoked potential index.
We studied four electrophysiological variables (bispectral index (BIS), 95% spectral edge frequency (SEF), median frequency (MF) and auditory evoked potential index (AEP index) in 10 patients during emergence from anaesthesia. We compared correlation of the signals with gradually decreasing calculated blood propofol concentrations, and evaluated the signal differences between preinduction and e...
متن کاملBispectral index monitoring during electroconvulsive therapy under propofol anaesthesia.
BACKGROUND The accuracy of the bispectral index (BIS) as a monitor of consciousness has not been well studied in patients who have abnormal electroencephalograms (EEG). METHODS We studied the changes in BIS, its subparameters, and spectral entropy of the EEG during 18 electroconvulsive treatments under propofol and succinylcholine anaesthesia. A single bifrontal EEG, and second subocular chan...
متن کاملRelationship between bispectral index, auditory evoked potential index and effect-site EC50 for propofol at two clinical end-points.
BACKGROUND Many anaesthetists are deterred from using total i.v. anaesthesia because of uncertainty over the concentration of propofol required to prevent awareness. We predicted blood and effect-site concentrations of propofol at two clinical end-points: loss of consciousness and no response to a painful stimulus. METHODS Forty unpremedicated Caucasian patients were anaesthetized with i.v. p...
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ژورنال
عنوان ژورنال: Anaesthesia
سال: 2002
ISSN: 0003-2409
DOI: 10.1046/j.0003-2409.2001.02446.x